Description

The Method
The test is based on a change of ammonia level in a patient’s mouth cavity air. H.pylori produces large amounts of urease, which degrades urea to ammonia. The ammonia is detected in the mouth cavity air by a change of the indicator tube color from yellow or orange to blue, violet or grey-green. The analysis consists of 2 parts. In Part I the basal ammonia level is detected. In Part II the load ammonia level is detected. After that the basal and load levels are compared and the conclusion regarding the H.pylori infection presence is made.

Warnings and Precautions
For in vitro diagnostic use only. The indicator tube is a single-use device. Do not use device beyond the expiry date. Discard the used devices as potentially infected waste according to the local and national regulations.

Preparations before the Test
1. The test is to be performed on an empty stomach: it is necessary to exclude taking food and water before the test. The last meal should be no less than 12 hours before the test. The last meal should be “light”: it’s necessary to avoid such products as meat, fish and mushrooms.
2. The test can be fulfilled: • 4-6 weeks after antibacterial therapy; • 2 weeks after last dose of antisecretory agents, anti-inflammation agents, acid inhibiting drugs (PPI or H2 blockers), bismuth drugs and analgetics.
3. It’s necessary to avoid strong alcohol for 3 days before the test.
4. It’s necessary to avoid legumes (such as peas, kidney beans, lentil, soy) for 3 days before the test.
5. It’s necessary to avoid chewing gum on the test day.
6. It’s necessary to avoid smoking for 3 hours before the test. It is necessary to brush teeth and rinse mouth cavity thoroughly after smoking.
7. It’s necessary to brush teeth and rinse mouth cavity thoroughly before the test.